MRI-based radiomics signature for pretreatment prediction of pathological response to neoadjuvant chemotherapy in osteosarcoma: a multicenter study.
Haimei ChenXiao ZhangXiaohong WangXianyue QuanYu DengMing LuQingzhu WeiQiang YeQuan ZhouZhiming XiangChanghong LiangWei YangYinghua ZhaoPublished in: European radiology (2021)
• The radiomics signature based on multicenter contrast-enhanced MRI was useful to predict response to NAC. • The prediction model obtained with the LASSO-LR classifier achieved the best performance. • The baseline clinical characteristics were not associated with response to NAC.
Keyphrases
- contrast enhanced
- neoadjuvant chemotherapy
- diffusion weighted
- magnetic resonance imaging
- magnetic resonance
- transcription factor
- computed tomography
- locally advanced
- diffusion weighted imaging
- lymph node
- sentinel lymph node
- rectal cancer
- dual energy
- clinical trial
- cross sectional
- early stage
- genome wide analysis
- lymph node metastasis