Soluble CD163 Changes Indicate Monocyte Association With Cognitive Deficits in Parkinson's Disease.
Sara Konstantin NissenSara Almeida FerreiraMarlene Christina NielsenClaudia SchulteKalpana ShrivastavaDorle HennigAnders EtzerodtJonas Heilskov GraversenDaniela BergWalter MaetzlerAnne PanhelainenHolger Jon MøllerKathrin BrockmannMarina Romero-RamosPublished in: Movement disorders : official journal of the Movement Disorder Society (2020)
Our data present sCD163 as a potential cognition-related biomarker in PD and suggest a role for monocytes in both peripheral and brain immune responses. This may be directly related to alpha-synuclein's proinflammatory capacity but could also have consequences for alpha-synuclein processing. © 2020 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.