TET1-Lipid Nanoparticle Encapsulating Morphine for Specific Targeting of Peripheral Nerve for Pain Alleviation.

Hongmei YangZhongqi LiuFan LiuHaixuan WuXiaoyan HuangRong HuangPhei Er SawMinghui Cao

Published in: International journal of nanomedicine (2024)

Our study presents a targeted lipid nanoparticle system for peripheral neural delivery of morphine. We anticipate Tet1-LNP (morphine) will offer a safe formulation for chronic neuropathic pain treatment, and promise further development for clinical applications.

Keyphrases

neuropathic pain
peripheral nerve
spinal cord
spinal cord injury
cancer therapy
drug delivery
fatty acid
chronic pain
iron oxide
pain management
big data
machine learning
combination therapy