Circular RNA expression profiling in the fetal side of placenta from maternal polycystic ovary syndrome and circ_0023942 inhibits the proliferation of human ovarian granulosa cell.
Chengcheng ZhaoYu ZhouXia ShenMin GongYingfei LuChao FangJianquan ChenRong JuPublished in: Archives of gynecology and obstetrics (2020)
Maternal PCOS impairs circ_0023942 expression in fetus. Overexpression of circ_0023942 inhibits human ovarian granulosa cell proliferation possibly via regulating CDK-4.
Keyphrases
- polycystic ovary syndrome
- cell proliferation
- insulin resistance
- endothelial cells
- induced pluripotent stem cells
- cell cycle
- pluripotent stem cells
- birth weight
- single cell
- gene expression
- adipose tissue
- transcription factor
- physical activity
- pregnant women
- genome wide
- type diabetes
- dna methylation
- bone marrow
- skeletal muscle
- weight loss