Clinical impact of androgen receptor-suppressing miR-146b expression in papillary thyroid cancer aggressiveness.

Chen-Kai ChouShun-Yu ChiYi-Yung HungYi-Chien YangHung-Chun FuJia-He WangChueh-Chen ChenHong-Yo Kang

Published in: The Journal of clinical endocrinology and metabolism (2023)

To sum up, miR-146b is a molecular target of AR transcriptional repression, therefore, AR suppresses miR-146b expression to reduce PTC tumor aggressiveness.

Keyphrases

papillary thyroid
lymph node metastasis
poor prognosis
signaling pathway
binding protein
long non coding rna
transcription factor
oxidative stress