IFN-γ: The T cell's license to kill stem cells in the inflamed intestine.

Published in: Science immunology (2020)

IFN-γ produced by T cells directly induces intestinal stem cell death upon inflammation-induced intestinal injury (see the related Research Article by Takashima et al.).

Keyphrases

stem cells
cell death
dendritic cells

immune response
oxidative stress
diabetic rats

high glucose
drug induced
cell therapy

endothelial cells
mesenchymal stem cells
cell proliferation