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IFN-γ: The T cell's license to kill stem cells in the inflamed intestine.

Kai KretzschmarHans Clevers
Published in: Science immunology (2020)
IFN-γ produced by T cells directly induces intestinal stem cell death upon inflammation-induced intestinal injury (see the related Research Article by Takashima et al.).
Keyphrases
  • stem cells
  • cell death
  • dendritic cells
  • immune response
  • oxidative stress
  • diabetic rats
  • high glucose
  • drug induced
  • cell therapy
  • endothelial cells
  • mesenchymal stem cells
  • cell proliferation