Login / Signup

Comparison of Adverse Events Between PARP Inhibitors in Patients with Epithelial Ovarian Cancer: A Nationwide Propensity Score Matched Cohort Study.

Gwan Hee HanHae-Rim KimHee YunJae-Hoon KimHanbyoul Cho
Published in: Targeted oncology (2024)
No differences were observed among the PARPi during first-line maintenance treatment. However, in the second-line maintenance treatment, significant differences were observed in the risk of experiencing CEIs, dose alteration possibilities, and discontinuation of PARPi between niraparib and olaparib (tablets). Moreover, our findings suggest that an age of 60 years may be a critical factor in selecting PARPi to reduce CEI incidence.
Keyphrases
  • dna damage
  • risk factors
  • dna repair
  • combination therapy
  • oxidative stress
  • cross sectional