The Population-level Effect of Adjuvant Therapies on Breast Cancer Recurrence: Application of the Trend-in-Trend Design.

Lindsay J CollinLance A WallerDeirdre P Cronin-FentonThomas P AhernMichael GoodmanLauren E McCulloughAnders KjærsgaardKirsten M WoolpertRebecca A SillimanPeer M ChristiansenBent EjlertsenHenrik Toft SørensenTimothy L Lash

Published in: Epidemiology (Cambridge, Mass.) (2024)

We demonstrated how novel pharmacoepidemiologic analytic designs can be used to evaluate the routine clinical care and effectiveness of therapeutic advancements in a population-based setting while considering some limitations of the approach.

Keyphrases

healthcare
randomized controlled trial
palliative care
early stage
systematic review
clinical practice
quality improvement
pain management
chronic pain
breast cancer risk