Relation Between Fatigue and ACR Response in Patients With Psoriatic Arthritis Treated With Tumor Necrosis Factor Inhibitor Therapy: A Population-based Cohort Study.
Tanja Schjødt JørgensenMarie SkougaardRebekka Lund HansenChristine BallegaardPhilip MeaseVibeke StrandLene DreyerLars Erik KristensenPublished in: The Journal of rheumatology (2020)
Fatigue remains a dominating symptom after TNFi treatment, and is associated with higher baseline disease activity, pain, and HAQ scores; more comorbidities; and increased risk of TNFi treatment discontinuation in a cohort of Danish patients with PsA. The agreement between ACR and VAS fatigue responses is weak to moderate, suggesting heterogeneity between experienced fatigue and joint inflammation.
Keyphrases
- disease activity
- rheumatoid arthritis
- sleep quality
- systemic lupus erythematosus
- chronic pain
- oxidative stress
- ankylosing spondylitis
- pain management
- rheumatoid arthritis patients
- mesenchymal stem cells
- juvenile idiopathic arthritis
- depressive symptoms
- spinal cord
- replacement therapy
- physical activity
- neuropathic pain
- newly diagnosed