Regional Changes in Brain Biomolecular Markers in a Collagen-Induced Arthritis Rat Model.
Aletta M E MillenTshiamo T MalulekeLeandrie PienaarFarhanah N SallieRadhini VeerappanPer E AndrenSooraj BajinathPublished in: Biology (2024)
CIA resulted in neuroinflammation concurrent with an apoptotic state and aberrant expression of neurotrophic factors and monoamines in the brain, suggestive of neurodegeneration.
Keyphrases
- resting state
- cerebral ischemia
- white matter
- poor prognosis
- cell death
- functional connectivity
- rheumatoid arthritis
- traumatic brain injury
- high glucose
- diabetic rats
- lipopolysaccharide induced
- drug induced
- cognitive impairment
- squamous cell carcinoma
- locally advanced
- anti inflammatory
- lps induced
- blood brain barrier
- oxidative stress
- brain injury
- tissue engineering