Acute pharmacodynamic effects of pimobendan in client-owned cats with subclinical hypertrophic cardiomyopathy.
Maureen S OldachYu UedaEric S OntiverosSamantha L FousseLance C VisserJoshua A SternPublished in: BMC veterinary research (2021)
In client-owned cats with HCM, pimobendan acutely increased left atrial function and mildly increased left ventricular systolic function. Left ventricular outflow tract velocity was increased after pimobendan. Pimobendan was well tolerated in the acute setting in cats with HCM. The findings of this prospective, acute-dosing study confirm previous findings in research animals and retrospective analyses and suggest that chronic dosing studies are safe and warranted.
Keyphrases
- hypertrophic cardiomyopathy
- left ventricular
- left atrial
- liver failure
- respiratory failure
- mitral valve
- heart failure
- acute myocardial infarction
- cardiac resynchronization therapy
- drug induced
- aortic stenosis
- aortic dissection
- blood pressure
- atrial fibrillation
- cross sectional
- extracorporeal membrane oxygenation
- case control