The Immunohistochemical Expression of MCM-3, -5, and -7 Proteins in the Uterine Fibroids.

Piotr RubiszLidia HirnleChristopher Kobierzycki

Published in: Current issues in molecular biology (2021)

Uterine fibroid cells have greater proliferative potential, as evaluated by expression of the Ki-67 antigen and MCMs, than unaltered myometrial cells of the uterine corpus. The expression of MCM-7 was found to have strong or moderate correlations in all assessed relations. In the context of the clinical data, as well evident proliferative potential of MCMs, further studies are strongly recommended.

Keyphrases

poor prognosis
induced apoptosis
cell cycle arrest
binding protein
long non coding rna
electronic health record
risk assessment
high intensity
big data
climate change
deep learning
pi k akt
case control