A Novel Algorithm for the Management of Inpatient COVID-19 Glucocorticoid-Induced Hyperglycemia.
Alexander B KarolNatalia VieraSelassie J OgyaaduDanielle BrooksNirali A ShahAnne S LinkerDavid W LamCarol J LevyGrenye O'MalleyPublished in: Clinical diabetes : a publication of the American Diabetes Association (2023)
Hyperglycemia in hospitalized patients with coronavirus disease 2019 (COVID-19) is linked to increased morbidity and mortality. This article reports on a novel insulin titration protocol for the management of glucocorticoid-induced hyperglycemia in hospitalized patients with COVID-19. Sixty-five patients with COVID-19 and glucocorticoid-induced hyperglycemia admitted after the protocol implementation were matched 1:1 to patients admitted before the treatment protocol rollout for analysis. In a large, diverse health system, the protocol achieved reductions in hypoglycemic events without increasing hyperglycemia or insulin use.
Keyphrases
- diabetic rats
- coronavirus disease
- oxidative stress
- randomized controlled trial
- high glucose
- type diabetes
- sars cov
- healthcare
- primary care
- emergency department
- mental health
- respiratory syndrome coronavirus
- metabolic syndrome
- quality improvement
- combination therapy
- insulin resistance
- skeletal muscle
- electronic health record
- replacement therapy