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Impact of Food Additive Titanium Dioxide on Gut Microbiota Composition, Microbiota-Associated Functions, and Gut Barrier: A Systematic Review of In Vivo Animal Studies.

Emanuele RinninellaCintoni MarcoPauline RaoulVincenzina MoraAntonio GasbarriniMaria Cristina Mele
Published in: International journal of environmental research and public health (2021)
Although the extrapolation of these results from animals to humans remains difficult, this review highlights the key role of gut microbiota in gut nanotoxicology and stimulates discussions on the safe TiO2 use in food and dietary supplements. This systematic review was registered at PROSPERO as CRD42020223968.
Keyphrases
  • systematic review
  • meta analyses
  • human health
  • randomized controlled trial
  • case control
  • risk assessment
  • climate change