The Regulatory Role of miR-107-Cdk6-Rb Pathway in Airway Smooth Muscle Cells in Asthma.
Yi XiongYani LuoTing YuwenJiana LiRongchang ChenFei ShiPublished in: Journal of asthma and allergy (2023)
The expression of miR-107 is down-regulated in serums of asthma patients and ASMCs of asthmatic mice. It plays a critical role in regulating the proliferation and migration of ASMCs via targeting Cdk6.
Keyphrases
- cell proliferation
- lung function
- long non coding rna
- chronic obstructive pulmonary disease
- end stage renal disease
- cell cycle
- poor prognosis
- long noncoding rna
- newly diagnosed
- chronic kidney disease
- transcription factor
- allergic rhinitis
- type diabetes
- patient reported outcomes
- metabolic syndrome
- air pollution
- drug delivery
- binding protein
- skeletal muscle