MicroRNA-1 Modulates Chondrocyte Phenotype by Regulating FZD7 of Wnt/β-Catenin Signaling Pathway.

Yang YangYawei WangHaobo JiaBing LiDan XingJiao Jiao Li

Published in: Cartilage (2020)

Inhibition of Wnt/β-catenin signaling by miR-1 in chondrocytes may attenuate the expression of genes that regulate the activity of catabolic enzymes. This finding may be useful for future investigations of molecular targets for OA treatment.

Keyphrases

cell proliferation
stem cells
poor prognosis
long non coding rna
long noncoding rna
current status
knee osteoarthritis
gene expression
binding protein
single molecule
bioinformatics analysis