Login / Signup

Conserved expression of vertebrate microvillar gene homologs in choanocytes of freshwater sponges.

Jesús F PeñaAlexandre AliéDaniel J RichterLingyu WangNoriko FunayamaScott A Nichols
Published in: EvoDevo (2016)
The available evidence suggests that microvilli evolved early in the prehistory of modern animals and have been repurposed to serve myriad functions in different cellular contexts. Detailed understanding of the sequence by which different microvilli-bearing cell/tissue types diversified will require further study of microvillar composition and development in disparate cell types and lineages. Of particular interest are the microvilli of choanoflagellates, ctenophores, and sponges, which collectively bracket the earliest events in animal evolution.
Keyphrases
  • single cell
  • poor prognosis
  • transcription factor
  • stem cells