ADAR1-mediated RNA-editing of 3'UTRs in breast cancer.

Eduardo A SagredoAlejandro BlancoAlfredo I SagredoPaola PérezGonzalo Sepúlveda-HermosillaFernanda MoralesBettina MüllerRicardo VerdugoKatherine MarcelainOlivier HarismendyRicardo Armisén

Published in: Biological research (2018)

Altogether, these results revealed a significant association between the mRNA editing in genes related to cancer-relevant pathways and clinical outcomes, suggesting an important role of ADAR1 expression and function in breast cancer.

Keyphrases

crispr cas
poor prognosis
papillary thyroid
binding protein
childhood cancer
genome wide
single cell
squamous cell
squamous cell carcinoma
lymph node metastasis
breast cancer risk
genome wide identification