Prospective Randomized Open-label Trial to evaluate risk faCTor management in patients with Unruptured intracranial aneurysms: Study protocol.
Mervyn D I VergouwenGabriel Je RinkelAle AlgraJens FiehlerHelmuth SteinmetzPeter VajkoczyFrans H RuttenSteffen LuntzDaniel HänggiNima EtminanPublished in: International journal of stroke : official journal of the International Stroke Society (2018)
The Prospective Randomized Open-label Trial to Evaluate risk faCTor management in patients with Unruptured intracranial aneurysms (PROTECT-U) is the first randomized trial to investigate if a medical strategy reduces the risk of rupture or growth of intracranial aneurysms in patients not undergoing preventive endovascular or neurosurgical aneurysm treatment. Clinical trial Registration: NCT03063541.
Keyphrases
- open label
- phase iii
- phase ii
- study protocol
- clinical trial
- double blind
- risk factors
- phase ii study
- randomized controlled trial
- placebo controlled
- end stage renal disease
- healthcare
- middle cerebral artery
- ejection fraction
- internal carotid artery
- coronary artery
- chronic kidney disease
- prognostic factors
- patient reported
- rectal cancer