Risk Factors for Fracture in Patients with Coexisting Chronic Kidney Disease and Type 2 Diabetes: An Observational Analysis from the CREDENCE Trial.

Tamara K YoungNigel D ToussaintGian Luca Di TannaClare ArnottCarinna HockhamAmy KangAletta E SchutteVlado PerkovicKenneth W MahaffeyRajiv AgarwalGeorge L BakrisDavid M CharytanHiddo J L HeerspinkAdeera LevinCarol PollockDavid C WheelerHong ZhangMeg J Jardine

Published in: Journal of diabetes research (2022)

Independent predictors of fracture were identified in the CREDENCE participants with type 2 diabetes and CKD. Fracture prediction was not improved by models built on alternative pathophysiology hypotheses compared with traditional osteoporosis predictors.

Keyphrases

chronic kidney disease
type diabetes
end stage renal disease
hip fracture
clinical trial
cardiovascular disease
study protocol
cross sectional
phase iii
glycemic control
adipose tissue