Folic Acid Treatment for Patients with Vascular Cognitive Impairment: A Systematic Review and Meta-Analysis.

Abdul GofirSamekto WibowoMuhammad HakimiDavid Dwi PuteraIrawan SatriotomoMustofa Mustofa

Published in: The international journal of neuropsychopharmacology (2021)

Our review shows the effectiveness of folic acid in lowering plasma homocysteine concentration after 6 months period compared to placebo. However, this effect is not accompanied by improvement in cognitive function.

Keyphrases

cognitive impairment
randomized controlled trial
systematic review
clinical trial
phase iii
open label
smoking cessation