Primary results of a randomized two-by-two factorial phase II trial comparing neoadjuvant chemotherapy with two and four courses of cisplatin/S-1 and docetaxel/cisplatin/S-1 as neoadjuvant chemotherapy for advanced gastric cancer.
Tsutomu HayashiTakaki YoshikawaKentaro SakamakiKazuhiro NishikawaKazumasa FujitaniKazuaki TanabeKazunari MisawaTakanori MatsuiAkira MikiHiroshi NemotoTetsu FukunagaYutaka KimuraJun HiharaPublished in: Annals of gastroenterological surgery (2020)
Considering high 3-year OS, four courses DCS has a value to be tested in a future phase III study to confirm superiority of neoadjuvant chemotherapy for locally advanced gastric cancer.