A trial of oral corticosteroids for persistent systemic and airway inflammation in severe asthma.

Keiji OishiTsunahiko HiranoRyo SuetakeSyuichiro OhataYoshikazu YamajiKosuke ItoNobutaka EdakuniKazuto Matsunaga

Published in: Immunity, inflammation and disease (2017)

In the patients with severe asthma, responses to systemic corticosteroids were variable in terms of FeNO and blood eosinophils. It was necessary to suppress both persistent eosinophilia and high FeNO for the improvement of asthma control.

Keyphrases

chronic obstructive pulmonary disease
clinical trial
lung function
phase iii
phase ii
randomized controlled trial
cystic fibrosis