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ST2 expression and release by the bronchial epithelium is downregulated in asthma.

Davinder KaurLatifa ChachiEdith GomezNicolas SylviusShailendra R SinghMohammadali Y RamshehRuth M SaundersChristopher E Brightling
Published in: Allergy (2020)
In asthma, bronchial epithelium protein expression of ST2 is decreased. Our in vitro findings suggest that this decrease might be a consequence of the pro-inflammatory environment in asthma or in response to viral infection.
Keyphrases
  • chronic obstructive pulmonary disease
  • lung function
  • allergic rhinitis
  • poor prognosis
  • cystic fibrosis
  • air pollution
  • binding protein