Integrated Metabolic Profiling and Transcriptional Analysis Reveals Therapeutic Modalities for Targeting Rapidly Proliferating Breast Cancers.
Chengheng LiaoCherise Ryan GlodowskiCheng FanJuan LiuKevin R MottAkash KaushikHieu VuJason W LocasaleSamuel K McBrayerRalph J DeBerardinisCharles M PerouYang ZhangPublished in: Cancer research (2022)
A multiomics strategy that integrates metabolic and gene expression profiling in patient tumor samples and animal models identifies effective pharmacologic approaches to target rapidly proliferating breast tumor subtypes.