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Integrated Metabolic Profiling and Transcriptional Analysis Reveals Therapeutic Modalities for Targeting Rapidly Proliferating Breast Cancers.

Chengheng LiaoCherise Ryan GlodowskiCheng FanJuan LiuKevin R MottAkash KaushikHieu VuJason W LocasaleSamuel K McBrayerRalph J DeBerardinisCharles M PerouYang Zhang
Published in: Cancer research (2022)
A multiomics strategy that integrates metabolic and gene expression profiling in patient tumor samples and animal models identifies effective pharmacologic approaches to target rapidly proliferating breast tumor subtypes.
Keyphrases
  • genome wide
  • gene expression
  • case report
  • dna methylation
  • single cell
  • cancer therapy
  • drug delivery
  • young adults
  • oxidative stress