The Importance of Extracellular Vesicle Screening in Gastric Cancer: A 2024 Update.
Vasile BintintanClaudia BurzIrena PinteaIoana Adriana MunteanDiana DeleanuIulia LupanGabriel SamașcaPublished in: Cancers (2024)
Extracellular vesicles, or EVs, are membrane-bound nanocompartments produced by tumor cells. EVs carry proteins and nucleic acids from host cells to target cells, where they can transfer lipids, proteomes, and genetic material to change the function of target cells. EVs serve as reservoirs for mobile cellular signals. The collection of EVs using less invasive processes has piqued the interest of many researchers. Exosomes carry substances that can suppress the immune system. If the results of exosome screening are negative, immunotherapy will be beneficial for GC patients. In this study, we provide an update on EVs and GC based on ongoing review papers and clinical trials.
Keyphrases
- induced apoptosis
- cell cycle arrest
- clinical trial
- end stage renal disease
- endoplasmic reticulum stress
- randomized controlled trial
- chronic kidney disease
- newly diagnosed
- oxidative stress
- prognostic factors
- study protocol
- dna methylation
- genome wide
- patient reported outcomes
- copy number
- mass spectrometry
- liquid chromatography