Ser9p-GSK3β Modulation Contributes to the Protective Effects of Vitamin C in Neuroinflammation.

Melania RuggieroAntonia CianciulliRosa CalvelloAnnalisa Porro Francesco De Nuccio Marianna Kashyrina Alessandro Miraglia Dario Domenico Lofrumento Maria Antonietta Panaro

Published in: Nutrients (2024)

This study evidenced that Vit C exerts an anti-inflammatory function in microglia, promoting the upregulation of the M2 phenotype through the activation of the Wnt/β-catenin signaling pathway.

Keyphrases

anti inflammatory
cell proliferation
signaling pathway
stem cells
inflammatory response
traumatic brain injury
poor prognosis
lipopolysaccharide induced
lps induced
neuropathic pain
spinal cord injury
blood brain barrier