Limited utility of adding 3T cervical spinal cord MRI to monitor disease activity in multiple sclerosis.
Timothy Reynold U LimSunitha P KumaranSuradech SuthiphosuwanRoland Dominic G JamoraAshley JonesAmy Wei LinJiwon OhAditya BharathaPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2024)
Routine brain and cervical SC-MRI detected new isolated CSLs in only < 2% of clinically stable pwMS. Developing new asymptomatic CSLs was associated with concomitant new BLs and did not confer an independent increased risk of relapse or disability worsening. Performing SC-MRI may not be warranted for routine monitoring in most pwMS, and performing only brain MRI may be sufficient to capture the vast majority of clinically silent disease activity.
Keyphrases
- disease activity
- systemic lupus erythematosus
- rheumatoid arthritis
- contrast enhanced
- multiple sclerosis
- rheumatoid arthritis patients
- magnetic resonance imaging
- ankylosing spondylitis
- spinal cord
- diffusion weighted imaging
- juvenile idiopathic arthritis
- clinical practice
- computed tomography
- resting state
- spinal cord injury
- subarachnoid hemorrhage