Sphingosine kinase 1 expression enhances colon tumor growth.

Hideki FuruyaYoshiko ShimizuPaulette M TamashiroKayoko IinoJacek BielawskiOwen T M ChanIan PaganoToshihiko Kawamori

Published in: Journal of translational medicine (2017)

SphK1 expression regulates the early stage of colon carcinogenesis and tumor growth, thus inhibition of SphK1 may be an effective strategy for colon cancer chemoprevention.

Keyphrases

early stage
poor prognosis
binding protein
long non coding rna