Effects of oxidized LDL versus IL-1ß/TNF-ɑ/INFɣ on human gingival mesenchymal stem cells properties.

Karim Mohamed Fawzy El-SayedElena MahlandtKristina SchlichtKim EnthammerJohannes TölleJuliane WagnerKatharina HartmannPeter R EbelingChristian GraetzMathias LaudesChristof E DörferDominik M Schulte

Published in: Journal of periodontal research (2024)

Within the current investigation's limitations, in contrast to cytokine-mediated inflammation, G-MSCs appear to be minimally responsive to oxLDL-mediated metabolic inflammation, with little negative effect on their differentiation attributes and significantly reduced cellular proliferation.

Keyphrases

mesenchymal stem cells
oxidative stress
umbilical cord
endothelial cells
rheumatoid arthritis
low density lipoprotein
signaling pathway
induced pluripotent stem cells
magnetic resonance imaging
cancer therapy
stem cells
cell therapy
pluripotent stem cells