HIF-1α expression in liver metastasis but not primary colorectal cancer is associated with prognosis of patients with colorectal liver metastasis.
Yuma WadaYuji MorineSatoru ImuraTetsuya IkemotoYu SaitoChie TakasuShinichiro YamadaMitsuo ShimadaPublished in: World journal of surgical oncology (2020)
HIF-1α expression in liver metastasis determines poor prognosis of CRLM patients. HSCs might play a key role in aggressive phenotypes of tumor cells.