A new digital droplet PCR method for looking at epigenetics in diffuse large B-cell lymphomas: The role of BMI1, EZH2, and USP22 genes.

Alessio Lusci GemignaniRobel PapottiRiccardo BombenValter GatteiSamantha PozziValentina DonatiStefania BettelliElisa FortiGiovanna MansuetoArianna Di NapoliMaria Christina CoxLeonardo FlenghiPietro RossiGuido VolpeDimitri DardanisClara BonoFrancesca GuerriniRiccardo MorgantiStefano SacchiSara Galimberti

Published in: International journal of laboratory hematology (2024)

High expression of BMI1 and of USP22 might be a poor prognostic factor in DLBCL, and might represent the target for novel inhibitors.

Keyphrases

prognostic factors
body mass index
poor prognosis
weight gain
long non coding rna
diffuse large b cell lymphoma
genome wide
single cell
high throughput
low grade
long noncoding rna
binding protein
genome wide identification
physical activity
dna methylation
genome wide analysis
real time pcr