Prediction of autoimmune connective tissue disease in an at-risk cohort: prognostic value of a novel two-score system for interferon status.

Md Yuzaiful Md YusofAntonios PsarrasYasser Mohamed El-SherbinyElizabeth M A HensorKatherine DuttonSabih Ul-HassanAhmed S ZayatMohammad ShalbafAdewonuola AlaseMiriam WittmannPaul EmeryEdward M Vital

Published in: Annals of the rheumatic diseases (2018)

A two-factor interferon score and family history predict progression from ANA positivity to AI-CTD. These interferon scores may allow stratification of individuals At-Risk of AI-CTD permitting early intervention for disease prevention and avoid irreversible organ damage.

Keyphrases

dendritic cells
artificial intelligence
randomized controlled trial
oxidative stress
multiple sclerosis
deep learning