Hypoxia Drives Centrosome Amplification in Cancer Cells via HIF1α-dependent Induction of Polo-Like Kinase 4.
Karuna MittalJaspreet KaurShaligram SharmaNivya SharmaGuanhao WeiIshita ChoudharyPrecious Imhansi-JacobNagini MagantiShrikant D PawarPadmashree RidaMichael S TossMohammed AleskandaranyEmilius A M JanssenHåvard SøilandMeenakshi V GuptaMichelle D ReidEmad A RakhaRitu AnejaPublished in: Molecular cancer research : MCR (2022)
Hypoxia drives CA in cancer cells by regulating expression of PLK4, uncovering a novel HIF1α/PLK4 axis.