Spatially resolved multimarker evaluation of CD274 (PD-L1)/PDCD1 (PD-1) immune checkpoint expression and macrophage polarisation in colorectal cancer.
Hanna ElomaaMaarit AhtiainenSara A VäyrynenShuji OginoJonathan A NowakMai Chan LauOlli HelminenErkki-Ville WirtaToni T SeppäläJan BöhmJukka-Pekka MecklinTeijo KuopioJuha P VäyrynenPublished in: British journal of cancer (2023)
T cells), and associations with favourable clinical outcome. Our comprehensive multimarker assessment could enhance the understanding of immune checkpoints in the tumour microenvironment and promote the development of improved immunotherapies.