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Spatially resolved multimarker evaluation of CD274 (PD-L1)/PDCD1 (PD-1) immune checkpoint expression and macrophage polarisation in colorectal cancer.

Hanna ElomaaMaarit AhtiainenSara A VäyrynenShuji OginoJonathan A NowakMai Chan LauOlli HelminenErkki-Ville WirtaToni T SeppäläJan BöhmJukka-Pekka MecklinTeijo KuopioJuha P Väyrynen
Published in: British journal of cancer (2023)
T cells), and associations with favourable clinical outcome. Our comprehensive multimarker assessment could enhance the understanding of immune checkpoints in the tumour microenvironment and promote the development of improved immunotherapies.
Keyphrases
  • poor prognosis
  • stem cells
  • adipose tissue
  • binding protein
  • long non coding rna