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Review article: iron disturbances in chronic liver diseases other than haemochromatosis - pathogenic, prognostic, and therapeutic implications.

Albert J Czaja
Published in: Alimentary pharmacology & therapeutics (2019)
Iron dysregulation is common in chronic liver diseases other than hereditary haemochromatosis, and has been associated with liver toxicity and poor prognosis. Further evaluation of iron overload as a co-morbid factor should identify the key pathogenic disturbances, establish the risk threshold for iron toxicity, and promote molecular interventions.
Keyphrases
  • poor prognosis
  • iron deficiency
  • long non coding rna
  • oxidative stress
  • physical activity
  • weight loss