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Randomized, Blinded, Controlled Clinical Trial of Polylactide-Collagen Scaffold in Treatment of Shoulder Osteochondritis Dissecans in Dogs.

Helka HeikkiläVilma ReunanenHeli K HyytiäinenJouni J T JunnilaOuti Laitinen-VapaavuoriPauli Keränen
Published in: Veterinary and comparative orthopaedics and traumatology : V.C.O.T (2024)
 The results suggest that COPLA scaffold slowed down the development of OA at 6 months but it did not improve the clinical recovery or prevent OA in dogs with shoulder OCD in long-term follow-up at 1.5 years compared with arthroscopic debridement only. Regardless of the treatment method, clinical recovery was good, but OA developed in the majority of dogs.
Keyphrases
  • clinical trial
  • knee osteoarthritis
  • double blind
  • open label
  • rotator cuff
  • tissue engineering
  • phase ii
  • randomized controlled trial
  • phase iii
  • combination therapy
  • replacement therapy