Galectin-3-upregulated FAK promotes angiogenesis through oral lichen planus-activated fibroblasts.

Xiaoheng XuQian MiSiting ChenYang LiuXiaoqin XiongYinshen YangQian LiShuhua LiWenxia Meng

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2024)

The upregulation of Galectin-3 expression in oral lichen planus is associated with angiogenesis, and the oral lichen planus-activated fibroblasts promote human umbilical vein vascular endothelial cells migration and tube-forming differentiation through VEGFR2/FAP activation by Galectin-3.

Keyphrases

endothelial cells
vascular endothelial growth factor
poor prognosis
high glucose
binding protein