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Diamond Nanofilm Normalizes Proliferation and Metabolism in Liver Cancer Cells.

Malwina SosnowskaMarta KutwinBarbara StrojnyMateusz WierzbickiDominik CysewskiJarosław SzczepaniakMateusz FicekPiotr KoczońSlawomir JaworskiAndre ChwalibogEwa Sawosz
Published in: Nanotechnology, science and applications (2021)
In vitro studies demonstrated the antiproliferative properties of nfND against C3A liver cancer cells. At the same time, the need to personalize potential therapy was indicated due to the differential protein synthetic responses in C3A vs HepG2 cells. We documented that nfND is a source of signals capable of normalizing the expression of many intracellular proteins involved in the transformation to non-cancerous cells.
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