Incidence of muscle symptoms in placebo arm among statin-intolerant patients: a systematic review with meta-analysis.
Rita LouroRyan Gouveia E MeloJorge RuivoAna G AlmeidaFausto J PintoDaniel CaldeiraPublished in: Expert review of cardiovascular therapy (2023)
In patients previously labeled as statin-intolerant, about a fifth of the patients exhibited muscle symptoms when receiving a placebo. This highlights the importance of ruling out non-statin-related symptoms to further optimize statin therapy for cardiovascular risk improvement.