Reduced-Dose Radiation Therapy for HPV-Associated Oropharyngeal Carcinoma (NRG Oncology HN002).
Sue S YomPedro Torres-SaavedraJimmy J CaudellJohn N WaldronMaura L GillisonPing XiaMinh T TruongChristina KongRichard JordanRathan M SubramaniamMin YaoChristine H ChungJessica L GeigerJason W ChanBrian O'SullivanDukagjin M BlakajLoren K MellWade L ThorstadChristopher U JonesRobyn N BanerjeeChristopher LominskaQuynh-Thu LePublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2021)
The IMRT + C arm met both prespecified end points justifying advancement to a phase III study. Higher rates of grade ≥ 3 acute AEs were reported in the IMRT + C arm.