Characteristics of Japanese patients with Leber's hereditary optic neuropathy and idebenone trial: a prospective, interventional, non-comparative study.

Hiroto IshikawaYoichiro MasudaHitoshi IshikawaKeigo ShikisimaToshiaki GosekiTakeshi KezukaMasahiko TeraoAtsushi MiyazakiKenji MatsumotoHiroki NishikawaFumi GomiOsamu Mimura

Published in: Japanese journal of ophthalmology (2020)

Idebenone's potential and favorable safety profile were confirmed in Japanese LHON patients. However, this study had no placebo group; therefore, we need to undertake a prospective intervention study to further investigate the therapeutic effects of Idebenone in Japanese LHON patients.

Keyphrases

end stage renal disease
newly diagnosed
chronic kidney disease
ejection fraction
randomized controlled trial
prognostic factors
peritoneal dialysis
clinical trial
patient reported outcomes
patient reported
open label