A patient-centered, combination intervention to support adherence to HIV pre-exposure prophylaxis during pregnancy and breastfeeding: a randomized pilot study in Malawi.

Benjamin H ChiFriday SaidiLauren A GraybillTwambilile PhangaKatie R MollanK Rivet AmicoKellie FreebornNora E RosenbergLauren M HillTwaambo HamoongaBrian RichardsonThokozani KaluaSam PhiriWilbroad Mutale

Published in: Journal of acquired immune deficiency syndromes (1999) (2023)

In this randomized trial of PrEP adherence support, retention was high, but less than one-third of participants had pharmacologically confirmed adherence of >4 doses/week. Future research should focus on antenatal and postnatal HIV prevention needs and their alignment across the PrEP continuum, including uptake, persistence, and adherence.

Keyphrases

men who have sex with men
preterm infants
hiv testing
hiv positive
randomized controlled trial
glycemic control
pregnant women
antiretroviral therapy
hiv infected
hepatitis c virus
human immunodeficiency virus
clinical trial
hiv aids
preterm birth
skeletal muscle