HSF1 expression in tumor-associated macrophages promotes tumor cell proliferation and indicates poor prognosis in esophageal squamous cell carcinoma.

Yiqiu LiQifan LiJiasheng LiuYuying HuangJinzhu MaoGe Zhang

Published in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2022)

The up-regulation of HSF1 was more rapid and could affect the proliferation of tumor cells in IL4-induced macrophages. The expression of HSF1 in TAMs can also serve as a marker for ESCC prognosis.

Keyphrases

poor prognosis
long non coding rna
heat shock
cell proliferation
high glucose
cell cycle