Mesothelin expression in gynecologic carcinosarcoma: clinicopathological significance and correlation with HER2 expression.

Rui Kitadai Tadaaki Nishikawa Hiroshi Yoshida Chiharu Mizoguchi Kasumi Yamamoto Tomoyasu Kato Kan Yonemori

Published in: Journal of gynecologic oncology (2023)

MSLN expression is widely observed in gynecological carcinosarcomas. Moreover, high-MSLN expression is a favorable prognostic factor for UCS. MSLN could be a promising therapeutic target for UCS, even in the era of anti-HER2 therapy.

Keyphrases

poor prognosis
prognostic factors
long non coding rna
bone marrow
replacement therapy