Thymoquinone Preserves Pancreatic Islets Structure Through Upregulation of Pancreatic β-Catenin in Hypothyroid Rats.

Khadija FaddladdeenSoad Shaker AliSafia BahshwanNasra Naeim Ayuob

Published in: Diabetes, metabolic syndrome and obesity : targets and therapy (2021)

TQ alleviated PTU-induced hypothyroidism changes in insulin homeostasis and pancreatic β cells mostly through its antioxidant effect as well as up-regulation of pancreatic β-catenin expression.

Keyphrases

poor prognosis
cell proliferation
epithelial mesenchymal transition
induced apoptosis
oxidative stress
signaling pathway
cell cycle arrest
diabetic rats
metabolic syndrome
adipose tissue
skeletal muscle
drug induced
insulin resistance
endoplasmic reticulum stress
smoking cessation