MicroRNA-29c mediates initiation of gastric carcinogenesis by directly targeting ITGB1.

Tae-Su HanKeun HurGuorong XuBoram ChoiYoshinaga OkugawaYuji ToiyamaHiroko OshimaMasanobu OshimaHyuk-Joon LeeV Narry KimAaron N ChangAjay GoelHan-Kwang Yang

Published in: Gut (2014)

MiR-29c acts as a tumour suppressor in GC by directly targeting ITGB1. Loss of miR-29c expression is an early event in the initiation of gastric carcinogenesis and may serve as a diagnostic and therapeutic biomarker for patients with GC.

Keyphrases

long non coding rna
cell proliferation
poor prognosis
long noncoding rna
cancer therapy
gas chromatography
binding protein
drug delivery