Login / Signup

A simple and effective method for simulating nested exchangeable correlated binary data for longitudinal cluster randomised trials.

Rhys A BowdenJessica KaszaAndrew B Forbes
Published in: BMC medical research methodology (2024)
This simulation method is the first to allow for practical and efficient simulation of large datasets of binary outcomes with the commonly used nested exchangeable correlation structure. This will allow for much more effective testing of designs and inference methods for longitudinal cluster randomised trials with binary outcomes.
Keyphrases
  • clinical trial
  • open label
  • ionic liquid
  • double blind
  • study protocol
  • cross sectional
  • case control
  • single cell
  • electronic health record
  • type diabetes
  • big data
  • rna seq
  • adipose tissue