Vasomotor symptoms and the homeostatic model assessment of insulin-resistance in Korean postmenopausal women.
Dae Hui KwonJu Hak LeeKi-Jin RyuHyun-Tae ParkTak KimPublished in: Obstetrics & gynecology science (2016)
The aim of this cross-sectional study was to evaluate the association between vasomotor symptoms (VMS) and insulin resistance, which can be postulated by the homeostatic model assessment (HOMA) index. This study involved 1,547 Korean postmenopausal women (age, 45 to 65 years) attending a routine health check-up at a single institution in Korea from January 2010 to December 2012. A menopause rating scale questionnaire was used to assess the severity of VMS. The mean age of participants was 55.22±4.8 years and 885 (57.2%) reported VMS in some degree. The mean HOMA index was 1.79±0.96, and the HOMA index increased with an increase in severity of VMS (none, mild, moderate and severe) in logistic regression analysis (β=0.068, t=2.665, P =0.008). Insulin resistance needs to be considered to understand the linkage between VMS and cardiometabolic disorders.
Keyphrases
- postmenopausal women
- insulin resistance
- bone mineral density
- adipose tissue
- metabolic syndrome
- type diabetes
- high fat diet
- healthcare
- polycystic ovary syndrome
- skeletal muscle
- mental health
- sleep quality
- psychometric properties
- cross sectional
- genome wide
- clinical practice
- high intensity
- health information
- social media
- depressive symptoms
- glycemic control
- hepatitis c virus
- health promotion