Probing Human Heart TCA Cycle Metabolism and Response to Glucose Load using Hyperpolarized [2- 13 C]Pyruvate MR Spectroscopy.

Hsin-Yu ChenJeremy W GordonNicholas DworkBrian T ChungAndrew RiselliSanjay SivalokanathanRobert A BokJames B SlaterDaniel B VigneronM Roselle AbrahamPeder Eric Zufall Larson

Published in: medRxiv : the preprint server for health sciences (2023)

C]pyruvate. Cardiac metabolite measurement in the fasting/fed states provides information on cardiac metabolic flexibility and the acetylcarnitine pool.

Keyphrases

left ventricular
blood glucose
endothelial cells
single molecule
heart failure
high resolution
insulin resistance
magnetic resonance
induced pluripotent stem cells
health information
contrast enhanced
pluripotent stem cells
mass spectrometry
adipose tissue
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skeletal muscle